Cooperating mutations: joint forces, novel vulnerabilities
نویسندگان
چکیده
منابع مشابه
The Effect of High Heel Shoes on Tibiofemoral and Patellofemoral joint Contact Forces and Muscle Forces
Introduction: High heel shoes affect the knee joint and can cause arthritis in the tibiofemoral (TFJ) and patellofemoral joints (PFJ). There is a dearth of research investigating the contact forces of TFJ and PFJ. Therefore, the purpose of this study was to assess the effect of high heel shoes on muscle forces as well as TFJ, and PFJ contact forces during walking. Materials & Methods: A tot...
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The introduction of highly selective ABL-tyrosine kinase inhibitors (TKIs) has revolutionized therapy for chronic myeloid leukemia (CML). However, TKIs are only efficacious in the chronic phase of the disease and effective therapies for TKI-refractory CML, or after progression to blast crisis (BC), are lacking. Whereas the chronic phase of CML is dependent on BCR-ABL, additional mutations are r...
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We estimated the patellofemoral joint forces generated during pedaling on a bicycle ergometer. Our calculations were based on measurements from a force transducer mounted on the pedal, 16-mm cine-film sequences, and biomechanical models of the cycling motion and of the patellofemoral joint. Six healthy male subjects cycled at different work loads, pedaling rates, saddle heights, and pedal foot ...
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ژورنال
عنوان ژورنال: Blood
سال: 2020
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.2019004679